This article has helped me a lot - it tells you exactly how the N75 works, and what it does.
http://forums.audiworld.com/showthread.php?t=1476692
pay particular attention to the last 4 lines of the article, which I feel apply if you are running a standard car.
On the other side of the argument - perhaps with increased boost (from a remap) the ECU's "messages" to the N75 are slightly askew from the factory configuration, and hence require tweaking? I'm not sure how accurate the factory calibration is, so wonder if you can get the N75's recalibrated???
EDIT: Re-reading this, if I've got my spare N75 at home, I'm going to fit it. If it doesn't cure the
problem, I'm going to adjust it via the screw and see what happens. I think the key fact from research is that the adjustment is NOT a huge amount - it's a tiny turn of the screw in either direction. And from my mechanical experience, to bleed MORE air off by lifting the plunger (thus increasing boost by keeping the wastegate actuator closed) the screw would need to be turned CLOCKWISE. To decrease boost (and push the plunger down further, opening the wastegate) it'd need to be turned ANTI-CLOCKWISE.
I can't see how an N75 itself becomes "faulty". If it had a component that could wear, and thus leak (such as the OEM DV rubber diaphragm) then it'd make sense - as this seems to involve solid plunger & screw adjustment may well cure the issue.
Note: It seems that the screw is GLUED in place. In order to adjust it, without breaking it, the N75 needs to be warm/hot.