I think it is worth it!
But maybe I am looking at it from a different point of view, because most of my experience is with n/a engines. Big gains are had instantly with remaps and bigger turbo's, but my personal preference (and I will say it ends up being a very expensive option) is to make the best of what you have first. I'd love to have the time and money to put my car on a dyno, get some base figures, then strip it down and blueprint it, gas flow the head (not necessarily big port, because that can knock torque figures back down), put it back together on the same standard map and dyno it again. I think the results would be quite noticeable (although certainly not value for money), and reliabilty would also be improved. This would then give you a fantastic base lump to work from, and make the most out of improved maps/induction & exhaust/cams/turbo, etc.