Well the biggest drive I've had was Brighton to Aberdeen in one go....
14 hours!!
7 hours just to get to Bristol!!
Anyway the only problems I had was a bit of leg cramp due to having the accelerator in the same position for long time, a numb butt and seriously tired (nothing to do with the car)
But all in all this was the end of a round Britian trip and we (wife and me) both found the car very pleasurable to drive. Our trip took us from
Aberdeen to Glasgow
Glasgow to Chipping Camden
Chipping Camden to St Austell (Cornwallshire)
St Austell to Portsmouth
Portsmouth to Brighton
THEN the biggy
Brighton to Aberdeen
From memory this trip was 2,000 + miles and was when the car had 10,000 miles on it and was seriously loving the car after that